Vanessa A. Tshichold

Clustering of PSA Data for Prostate Cancer Risk Classification and Its Explainability (2022)

Clustering of PSA Data for Prostate Cancer Risk Classification and Its Explainability (2022)

ETH

Abstract Prostate cancer is the most common malignancy affecting men and thesecond-leading cause of cancer death in the US. To detect and classify the risk of prostate cancer, doctors perform screening of prostate-specific antigen (PSA) levels. In this Thesis we want to improve thisrisk classification with unsupervised machine learning methods, as thelabels of cancer or no cancer may not reflect the truth; given that canceris only considered as such after confirmation by biopsy and thus possi-bly leaving some patients with cancer with the wrong label.